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List of Chapters

Chromatographic Approaches for Physicochemical Characterization of Compounds


Author(s): Natalija Nakov*; Jelena Acevska; Katerina Brezovska; Zoran Kavrakovski; Aneta Dimitrovska

It is well recognized that the physicochemical characterization of the compounds has primary importance during the early-stage drug screening, as well as for drug product formulation and drug quality control. The pharmaceutical research and industry require reliable and high-throughput methods for estimation for the critical physicochemical properties of the compounds such as ionization constant, lipophilicity, protein binding and permeability.