HEPATITIS: A GLOBAL HEALTH CONCERN

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ISBN: 978-93-87500-05-1

Open Access eBooks is inviting researchers working in the areas of hepatitis to submit their book chapter for the publication in volume 1 of an eBook Hepatitis: A Global Health Concern.

All book chapters undergo review process and published content is available in PDF & HTML formats.

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Copyright with Authors: As an eBook publisher, we serve researchers in publishing their valuable work after the stringent review process. However, copyright lies with authors. We follow the CC-BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/3.0/).

Different Formats: We provide eBooks in PDF and HTML formats. Both formats are user friendly and can act as per the user requirements. We put our efforts to provide other formats in future.

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Published Chapters:

Pathology of chronic hepatitis B and chronic hepatitis C


Author(s) : Faten Limaiem*; Asma Sassi; Saadia Bouraoui; Sabeh Mzabi

Chronic viral hepatitis is a syndrome of persisting hepatotropic viral infection usually associated with chronic inflammation, hepatocyte injury and progressive fibrosis. Chronic viral hepatitis is typically classified by the responsible infecting virus and modified by the extent of pathological injury and clinical compensation. Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent the two major causes of chronic liver disease and hepatocellular carcinoma. Despite inducing shared pathological events leading to oncogenic transformation, these two viruses present profound differences in their molecular features, life cycle and interplay with host factors, which significantly differentiate the prognostic and therapeutic approach to the related diseases. The liver injury present in chronic hepatitis may be variable, but the basic morphologic changes in all types of chronic viral hepatitis are similar. In this regard, the liver biopsy remains the gold standard and is an important tool in the evaluation of patients with liver disease.

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