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List of Chapters

Ace2 as Enzyme, Gateway and Therapeutic Target for the Covid-19


Author(s): Jose Luis Vique-Sanchez*

The ACE2 (angiotensin-converting enzyme 2) has become especially important in the development of COVID-19, which became the 2020 pandemic that has made it difficult for the world to deal with it. ACE2 began to have relevance since 2002, with the cases presented by the SARS-CoV, in this coronavirus outbreak, ACE2 was identified as the gateway for this virus, then MERS was presented, in which ACE2 also had an important role in enabling this virus to generate its infectious process.

Possible Use of Hydrogen Sulfide Donors to Treat The Consequences of SARS-CoV-2 Infection


Author(s): M.B. Evgen’ev

In the last decade, the gasotransmitter hydrogen sulphide (H2S) has received a lot of attention as a biological mediator of great importance in plant and animal kingdoms. It was demonstrated by numerous studies that H2S may participates in several vital processes in humans under normal conditions and in the case of various pathologies and stresses. H2S alongside with other signal molecules may provide neuroprotection, anti-inflammation, and importantly regulates cardiovascular state in humans.

How has COVID-19 Modified Training and Mood in Professional and Non-Professional Football Players?


Author(s): Abraham Garcia-Aliaga*; Daniel Mon-Lopez; Alberto Gines Bartolome; Diego Muriarte Solana

Coronavirus disease 2019 (COVID-19) has restricted freedom of movement with several countries ‘locked down’ worldwide. During this isolation period or quarantine, habits have been modified. This might have had negative effects on physiological variables but also influenced numerous emotional aspects, especially in elite athletes, which can have a negative impact on training and sleep quality, affecting their performance.

Characterization of the Interaction between COVID-19 and Cancer in Comorbid Patients


Author(s): Haocai Chang

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused great economic losses and life threats. Concomitantly, cancer overtakes cardiovascular disease to become leading cause of death. The effects and mechanisms of their interaction are rarely comprehensively summarized when a sudden disease (COVID-19) collides with an incurable disease (cancer), which has existed for a long time. Here, we’ll discuss the interaction between the COVID-19 and cancer in comorbid patients, and the full-scale understanding may better promote the clinical treatment of COVID-19 patients with concomitant cancer.

Antiviral Activity of Algae - Focusing on COVID-19


Author(s): Dorit Avni

Since 2019, the world has been coping with the Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This health threat has caused over four million deaths worldwide and its mortality rate continues to rise. There are currently no efficient therapies and/or vaccines that may help decrease this viral disease’s spread. Recent increased transmission of SARS-CoV-2 due to new mutations is raising concerns regarding vaccine efficacy. Additional approaches are needed to prevent SARS-CoV-2 infection and its implications. Boosting immunity has been a simple way to resist viral infection and limit fatalities. In this context, the use of nutraceuticals appears to be a potential solution.

COVID-19 in South America-Why Geometrical Risks Must be combined with Statistical Analysis to Improve Emergency Response


Author(s): Gauss M Cordeiro*; Jones O Albuquerque; Fernando Nobrega; Danillo Souza; Allisson Dantas; Daniel Lopez-Codina; Jose Luiz de Lima Filho

The new coronavirus was discovered in the Chinese province of Wuhan in late December 2019 and was named SARS-CoV 2 due to its similarity with SARS-CoV. Infections caused by this agent are now called COVID-19. Some of the most influential global websites on Coronavirus are “Worldometer”, “Our World in Data”, “Johns Hopkins Research Center”, and “World Health Organization (WHO) Coronavirus Dashboard”. Worldometer aggregates data from thousands of sources in real time and provides updated global COVID-19 statistics from 220 countries and territories such as total and new cases, total and new deaths, total and new recoveries, active and critical cases, total cases and total deaths per million, total tests, tests per million and population. Plots for the new daily cases and deaths and 3-day and 7-day moving averages are reported for each country.