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List of Chapters
Viscoelastic Point-of-Care Tests for Diagnosis of Fibrinogen Deficiency and Guidance of Fibrinogen Administration in Bleeding Patients
Author(s): Henry T Peng*
Thrombelastography (TEG; Haemonetics Corporation, Haemoscope Division, Nile, Illinois, USA) and rotational thromboelastometry (ROTEM; Tem Innovations GmbH, Munich, Germany succeeded by Instrumentation Laboratory, Bedford, Massachusetts, USA) are two point-of-care systems for hemostatic tests in whole blood. Both provide a global measure of hemostasis by quantitatively measuring the elasticity of blood from the beginning of coagulation to the ending with fibrinolysis. This includes the onset of clot formation, its progress, maximum clot strength, and clot stability, which provides important information about coagulation, fibrinolysis, and platelet function [3]. TEG and ROTEM can also identify the relative contributions of clotting factors, such as fibrinogen and platelets, to the overall coagulation process.
