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List of Chapters
The Role of Cancer Stem Cells (CSCs) in Gynecological Malignancies
Author(s): Janina Markowska*; Adam Huczynski; Zbigniew Kojs; Anna Markowska
Cancer in women is a global health problem. The identification of molecular mechanisms related to cancer development will enable the introduction of new effective therapies and oncological gynaecology. Cancer stem cells (CSCs) are one of the reasons behind the failure of oncological treatment. Most likely, the source of CSCs are somatic stem cells that have been transformed under the influence of various factors: genetic and epigenetic. CSCs are a small, specific subpopulation of cells which account for about 2% of the tumour mass but are resistant to treatment by standard methods: chemotherapy and radiation.
