Advances in Stroke Research

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Advances in Stroke Research

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Open Access eBooks is inviting researchers working in the areas of Stroke to submit their book chapter for the publication in volume 1 of an eBook Advances in Stroke Research

All book chapters undergo review process and published content is available in PDF & HTML formats.

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Published Chapters:

Recent Advances in Stroke Genetics


Author(s): Pradeep Kumar, PhD; Vishnu Swarup, PhD; Deepika Gupta, PhD; Himanshu Narayan Singh, PhD*; Achal Kumar Srivastava, MD, DM*

Stroke is a complex, polygenic, and multi-factorial neurological disorder caused by a combination of environmental, vascular and genetic factors [1]. Despite new developments in the treatment and prevention, stroke accounts for the primary cause of adult disability, the second leading cause of dementia and the third leading cause of mortality in most of the developed countries [2], [3]. In the last four decades, while it has been estimated a 42% decrease in stroke incidence in high-income countries, there is more than 100% increase in stroke incidence in low to middle income countries [4]. The National Commission on Macroeconomics and Health has projected that cases of stroke would increase from 1,081,480 in 2000 to 1,667,372 in 2015. According to WHO 80% of stroke cases in the world would occur in lower and middle income countries, mainly India and China by 2050 [5].

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