Gastric Cancer, also called as stomach Cancer is a cancer developing in the lining of the stomach. It is very difficult to identify in the early stages. In later stages, it spreads to lungs, liver and other parts of the body. Gastric Cancer can be treated with chemotherapy, surgery, targeted therapy and radiation therapy. Researchers working in these areas are requested to contribute your work as a book chapter for the publication in volume 2 of an eBook entitled OVERVIEW ON GASTRIC CANCER.
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Each volume contains around 5 or 6 book chapters providing information on latest advances in gastric cancer.
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Gastric cancer (GC) is the fifth most frequently diagnosed cancer and the third most common cause of cancer-related death globally. The prognosis of GC is poor, especially for patients with metastatic disease, for whom the 5-year overall survival (OS) rate is approximately 5%. For these patients, systemic therapy is the mainstay of treatment, and the goals of this therapy include palliation of symptoms and prolongation of survival.
Gastric carcinoma is one of the most common cancers and one of the most frequent causes of cancer death worldwide. The first step for a correct treatment in gastric cancer is to stage correctly the tumor, based on the TNM classification, in accordance with the classification of the American Joint Committee on Cancer (AJCC) staging system. The correct staging allows us to identify early or initial gastric tumors and choose the adequate treatment for each patient. This factor is one of the most important elements in the improvement of the results in the treatment of gastric cancer.
Gastric cancer is the fourth most common cancer worldwide and account for 1.5% of all new diagnoses and 5.2% of all cancer deaths. More than 139.000 new cases in Europe and more than 951.000 new cases worldwide were diagnosed in 2012. Gastric cancer is often diagnosed at an advanced stage due to the lack of symptoms at an early stage and lack of a screening schedule throughout most of the world. At the time of diagnosis 35% of patients present with evidence of distant metastases and 4-14% have metastatic disease to the liver. Furthermore in patients who present with local disease and undergo curative resection, the development of metastases is common, with hepatic metastases the commonest site of recurrence, occurring in over one third of patients.