Gastric Cancer, also called as stomach Cancer is a cancer developing in the lining of the stomach. It is very difficult to identify in the early stages. In later stages, it spreads to lungs, liver and other parts of the body. Gastric Cancer can be treated with chemotherapy, surgery, targeted therapy and radiation therapy. Researchers working in these areas are requested to contribute your work as a book chapter for the publication in volume 2 of an eBook entitled OVERVIEW ON GASTRIC CANCER.
All received book chapters undergo review process and are published on our website in PDF and HTML formats.
Each volume contains around 5 or 6 book chapters providing information on latest advances in gastric cancer.
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In recent decades, obesity has become a major public health problem. Based on the WHO's report, the prevalence of the obesity has increased more three times than what it was in 1975s  Moreover, it is among the first ten leading risk for worldwide death [1,2]. Substantially individuals are considered obese when their Body Mass Index (BMI) ≥30 kg/m2. Regarding to WHO's classification, obesity is classified as class I for a BMI between 30 and 34.9 kg/m2, class II for a BMI between 35 and 39.9 kg/m2, and class III for a BMI ≥ 40 kg/m2(extreme obesity) . Raised BMI is a major risk factor for many deadly problems, such as cancers, diabetes and cardiovascular disease [4,5]. This issue would project poorer outcome for obese individuals. There is a direct relationship between increasing the class of obesity and increasing the risk of death [5,6].
Even though there is a decline in worldwide incidence of Gastric Cancer (GC), the fact that its mortality rate is still high among other cancer types means we need more and advanced tools for prevention, early detection and effective treatment. The path that goes to all of these starts from better understanding the etiology at the molecular level, and finding new targets for the genetic alterations driving or accumulating during the progress of tumor evolution.
The incidence of gastric cancer varies widely worldwide, but it is considered the second most prevalent tumour. There are places of higher incidence like Japan and China with >20 cases per 100.000 habitants, and places with lower incidence like Northern Europe and Northern America with <10 cases per 100.000 habitants.